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nature.com
https://www.nature.com/articles/s41467-025-56618-y
Benchmarking the translational potential of spatial gene expression ...
Spatial transcriptomics has enabled the quantification of gene expression at spatial coordinates across a tissue, offering crucial insights into molecular underpinnings of diseases.
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mayoclinic.org
https://mayomagazine.mayoclinic.org/2025/10/spatia…
What Is Spatial Transcriptomics? - mayomagazine.mayoclinic.org
Now, thanks to an innovative technology known as spatial transcriptomics, Mayo Clinic experts are able to examine how genes are expressed in a tissue sample in three dimensions, providing unprecedented insights into cellular relationships and tissue structure.
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oup.com
https://academic.oup.com/nar/article/53/4/gkaf087/…
Precise gene expression deconvolution in spatial transcriptomics with ...
In this study, we present a novel method, termed spatial transcriptomic gene expression deconvolution (STged), designed for inferring cell-type-specific gene expression within individual spots.
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nih.gov
https://pubmed.ncbi.nlm.nih.gov/37814884/
Spatial Transcriptomics: Emerging Technologies in Tissue Gene ...
In this Perspective, we discuss the current status and advances in spatial transcriptomics technologies, which allow high-resolution mapping of gene expression in intact cell and tissue samples.
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sciencedirect.com
https://www.sciencedirect.com/science/article/pii/…
Spatial transcriptomics: Technologies, applications and experimental ...
The key difference between imaging-based and sequencing-based spatial transcriptomics technologies lies in their distinct approaches to determine the spatial localization and abundance of specific mRNA molecules within a tissue.
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arxiv.org
https://arxiv.org/html/2503.01347v1
Spatial Transcriptomics Analysis of Spatially Dense Gene Expression ...
Because slide images contain features at varying spatial scales, we extract a pyramidal feature map from the slide image, and progressively decode it into a high-resolution gene expression map, capturing hierarchical features for densely predicting the spatial gene expression.
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wikipedia.org
https://en.wikipedia.org/wiki/Spatial_transcriptom…
Spatial transcriptomics - Wikipedia
Spatial transcriptomics, or spatially resolved transcriptomics, is a method that captures positional context of transcriptional activity within intact tissue. [1]
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springer.com
https://link.springer.com/article/10.1186/s40246-0…
From bulk RNA sequencing to spatial transcriptomics: a ... - Springer
Conclusion Examining gene expression through these diverse RNA-seq modalities deepens our understanding of cellular processes, transcript modifications, tissue spatial organization, and gene expression variability.
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biorxiv.org
https://www.biorxiv.org/content/10.1101/2025.05.01…
17586966 - bioRxiv
Abstract: Spatial transcriptomics (ST) combines single-cell RNA-seq gene expression data with spatial coordinates to provide an accurate, 2D picture of gene expression across a tissue sample. With this technology, we can discover detailed RNA localization, study development, investigate the tumor microenvironment, and create a tissue atlas.
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nature.com
https://www.nature.com/articles/s41540-025-00624-9
Deciphering cell-fate trajectories using spatiotemporal single-cell ...
Single-cell and spatial omics technologies have provided high-resolution snapshots of gene expression, greatly expanding the capability to characterize cellular states.