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Germinal centers are high-speed evolution machines. Tiny clusters in the lymph nodes, germinal centers refine antibodies through mutation and expansion until they produce high-affinity B cells adapted ...
For more than half a century, many biologists have leaned on the neutral theory of molecular evolution to explain how DNA and proteins change over time. The idea grew from early work in the 1960s, ...
COLUMBUS, Ohio – The established conservation practice of relocating animals from large, genetically diverse populations to small communities of inbred endangered species may risk introducing more ...
Adverse genetic mutations can cause harm and are due to various circumstances. 'Jumping genes' are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA.
Adverse genetic mutations can cause harm and are due to various circumstances. "Jumping genes" are one cause of mutations, but cells try and combat them with a specialized RNA called piRNA. For the ...
New imaging reveals a built-in safeguard that allows B cell populations to rapidly expand in germinal centers without introducing deleterious mutations. Germinal centers are high-speed evolution ...