High-throughput screening (HTS) is an established method in drug discovery by which hundreds of thousands of compounds are screened in an automated fashion for activity as inhibitors or activators of ...

New Rochelle, NY, May 30, 2014—High throughput screening of compounds in live cells is a powerful approach for discovering new drugs, but the potential for cell toxicity must be considered. A novel ...

Engagement of intracellular targets is often critical to drug mechanisms. Establishing a target engagement (TE) profile is an important step in small- molecule drug discovery as well as chemical probe ...

In a recent study posted to the bioRxiv* preprint server, researchers discovered compounds able to inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) macrodomain 1 (Mac1) and ...

Developing new pharmaceuticals is a complex and costly process that requires innovation and efficiency. High-throughput immunoassays (HTIs) are an emerging technology poised to accelerate the drug ...

Partnership unites advanced screening solutions with world-class small molecule libraries.CHICAGO--(BUSINESS WIRE)--#AssayDevelopment--Peapod Bio Inc., a leader in innovative assay development and ...

Metrion Biosciences, today announced the launch of its validated, high-throughput NaV1.9 screening assay to advance discovery and development of novel pain therapeutics. Validated drug discovery assay ...

In a recent study posted to the bioRxiv* pre-print server, a team of researchers used an assay toolset for discovering new transmembrane protease serine 2 (TMPRSS2) inhibiting drug repurposing ...

Martin Clasby receives funding from the National Institutes of Health and Michigan Drug Discovery. Modern drug discovery is an expensive and complicated process. Hundreds of scientists and at least a ...