Medically reviewed by Anju Goel, MD Key Takeaways CD4 counts show how strong your immune system is; lower counts mean a ...

A panelist discusses how CD4 counts serve as measures of immune system status that typically increase by about 200 in the first year of antiretroviral therapy. Although there can be laboratory ...

CD4 tests are strongly recommended as the preferred method to identify advanced HIV disease among people living with HIV, the ...

Despite all the research into the benefits of antiretroviral therapy (ART), clinicians are still unable to answer some of the simplest questions patients routinely ask. Among the most common: What is ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Abnormal expansion of PD-1+ T lymphocytes may be a sign of lupus nephritis onset in patients with SLE. Elevated PD-1+CD4+ T cells represent an independent risk factor for lupus nephritis (LN) and may ...

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...

Hope for adults and children with cancers Camilla Jandus' team is currently preparing a clinical trial of TCR-engineered CD4-based cell therapy. The trial will include different types of cancer ...

In a person living with HIV, proviruses—strands of HIV DNA—are typically integrated into the T cell genome and become a ...

While chimeric antigen receptor (CAR) T cell therapy is an essential therapeutic option for prolonging survival in patients with relapsed or refractory non-Hodgkin lymphomas (NHL), profound immune ...