A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...
Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...
Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in ...
The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...
Researchers from the Tanenbaum group at the Hubrecht Institute have developed a new microscopy technique to observe how ribosomes function in cells. With this method, they can monitor individual ...
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New insights into how a molecular gatekeeper controls early protein modification
For years, ETH researchers have been investigating a molecular complex that plays a key role in protein synthesis. They have ...
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High-Resolution Technique Maps Ribosome Elongation Cycle
At one time or another, most of us have played with a flipbook, using our thumbs to rapidly flip a series of pictures to ...
Aging leads to a decline in cellular fitness and loss of optimal protein function. The mechanisms underlying how aging causes proteins to aggregate have not been fully understood. Using models of ...
Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.
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Nascent polypeptide-associated complex regulates early stages of protein formation
To ensure that protein production in our cells runs smoothly, the protein complex NAC slows down the rate of protein ...
This study is led by Prof. Ren Sun (Westlake University) and research fellow Yushen Du (Cancer Institute, the Second Affiliated Hospital, Zhejiang University School of Medicine). Myelotoxicity is the ...
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