Though studies evaluating the effects of posture on the absorption of drugs have been conducted, a systematized review revealed critical gaps in methodology. Of 18 original research articles selected ...

Congestive heart failure is a disease state distinguished by the regular presence of both renal and hepatic abnormalities in drug handling. One such abnormality involves flaws in the process of drug ...

Most drugs in the U.S. are taken orally because these oral dosage forms have a significant systemic effect on the body after being absorbed from different surfaces along the gastrointestinal tract ...

The effort to increase the number of druggable targets has coincided with a substantial expansion of the chemical property space in which new drug candidates can reside. As a consequence, contemporary ...

Membrane proteins are the target of most drugs currently on the market due to their relationship with the vast majority of diseases they are designed to treat. Drug activity depends on numerous ...

There exists a unique and clinically relevant time course of urinary drug delivery for a loop diuretic at which the natriuretic response is optimized. This rate of drug delivery resides on the steep ...