Collaborative work has developed a cell culture system that differentiates human pluripotent stem cells to amniotic ectoderm and surface ectoderm based on cell density. Research conducted by Dr Shota ...

Microscopy image of a PGA at day 8 showing the early tissues supporting the embryo, including the amniotic sac and the yolk sac-like structures, surrounded by (extra-embryonic) mesoderm tissue.

Receptor tyrosine kinases (RTKs) are a large group of integral membrane signaling molecules. Mutations in the RTK anaplastic lymphoma kinase (Alk) protein have been linked with non-Hodgkin lymphoma, ...

Scientists have grown a scalable new embryo-like model that unshrouds some mysteries of early human development, including blood cell formation, or hematopoiesis—a first for the field. In an article ...

A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development. The research, led by scientists at the ...

A cell aggregation of human pluripotent stem cells and amniotic ectoderm cells generated by the published culture method and mimicking the gastrulation event in human embryos. Gray: nuclei, Cyan: ...