Communication between oocytes and granulosa cells is essential for oocyte formation, dormancy, reawakening, and maturation. Researchers have demonstrated that a protein complex called the exocyst ...

The exocyst complex is a highly conserved hetero‐octameric assembly that plays a fundamental role in the tethering of secretory vesicles to the plasma membrane, thereby directing the process of ...

The exocyst, an octameric tethering complex and effector of Rho and Rab GTPases, facilitates polarized secretion in yeast and animals. Recent evidence implicates three plant homologs of exocyst ...

Polarized exocytosis is essential for many vital processes in eukaryotic cells, where secretory vesicles are targeted to distinct plasma membrane domains characterized by their specific lipid–protein ...

Like most Ras-family GTPases, Ral proteins have been implicated in the regulation of a diverse array of cellular processes, including oncogenic transformation, endocytosis and actin–cytoskeleton ...

Exocyst’s role in exocytosis. Credit: Seung-Hak Lee, medical student, School of Biological Sciences and Institute for Molecular Biology and Genetics, Seoul National University, Seoul, South Korea A ...

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology. Virtually every cell has a primary ...

Bicuspid aortic valve (BAV), the most common heart valve birth defect, is associated with genetic variation in human primary cilia during heart valve development, report researchers. Crucial to cilia ...

Tsukuba, Japan—In many mammals, a limited number of oocytes are responsible for producing the next generation. Oocytes grow within follicles, which consist of an oocyte and the surrounding granulosa ...