Now Niederweis and colleagues at the University of Alabama at Birmingham describe the mechanism of secretion and trafficking of that toxin, TNT, which is the major cytotoxicity factor for the pathogen ...
Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years. Now Niederweis ...
Figure 1: The enzymatic reaction and the eEF2–ETA c structure. Figure 4: Models of eEF2–toxin complexes based on the eEF2–ETA c –βTAD complex.
Heat-labile exotoxin of Pseudomonas aeruginosa has been purified and concentrated. Studies in mice have shown that the toxin affects protein synthesis in the liver within 3 hr of administration, ...
Exotoxin A ist bekannt als ein bedeutendes, virulentes Lektin aus dem Bakterium Pseudomonas aeruginosa. Die Molekülmasse beträgt 66,5 kDa. Das Polypeptid Exotoxin A besteht aus drei Domänen, von denen ...
A semicontinuous fermenter system was developed in which broth culture filtrates of Shigella dysenteriae type 1 yielded substantial amounts of exotoxin. Biologic activity of the exotoxin was ...
BIRMINGHAM, Ala. – Six years ago, Michael Niederweis, Ph.D., described the first known toxin of the deadly pathogen Mycobacterium tuberculosis (Mtb), an exotoxin that had gone undetected for 132 years ...
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