Jay Shendure is in the Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA, and at the Brotman Baty Institute for Precision Medicine, the Allen Discovery Center for ...

Only two weeks after fertilization, the first sign of the formation of the 3 axes of the human body (head/tail, ventral/dorsal, and right/left) begins to appear. At this stage, known as gastrulation, ...

As a human embryo grows, a set of molecules directs cells as they multiply and take on specific identities and spatial positions within the embryo. In one crucial step known as gastrulation, these ...

A new discovery by researchers challenges our current understanding of gastrulation, the most important stage of early embryonic development. When the zygote, or the fertilised egg, starts to develop, ...

When the zygote, or the fertilised egg, starts to develop, the soon forming inner cell mass, a cluster of cells that will eventually develop into the individual, retains its pluripotent stem cell ...