Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...
Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...
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RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model
Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.
Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.
Technologies at the Advanced Rodent Transgenics Laboratory include genome editing design and implementation and transgenic ...
Results reveal mechanism driving high blood pressure and point toward more precise therapies targeting communication between fat and blood vessels.
GemPharmatech, a global leader in preclinical research solutions and genetically-engineered mouse models, today announced a collaboration with Memorial Sloan Kettering Cancer Center (MSK) to ...
Pictured are two of Colossal's "woolly mice". Dallas-based biotech startup Colossal aims to bring the woolly mammoth back from extinction through genetic engineering. As part of that process, the ...
Fresh from raising $200 million, Colossal Biosciences announced it has genetically engineered the Colossal Woolly Mouse, with a warm coat taken from the genes of the extinct woolly mammoth. Dallas and ...
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