Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...
Taconic Biosciences, a global leader in providing disease specific rodent model solutions and related services, and Cyagen Biosciences, an AI-enabled CRO company specializing in custom genetically ...
Researchers identify bone-forming cells as the driver of scoliosis caused by a genetic disorder, which can be prevented ...
Using CRISPR-based technologies, the MoDeL team introduces precise genetic modifications in mice, enabling researchers to uncover how mammalian genes maintain health and contribute to disease.
GemPharmatech's antibody discovery platform aims to accelerate development of next-generation cancer therapies SAN DIEGO, Oct. 22, 2025 /PRNewswire/ -- GemPharmatech, a global leader in preclinical ...
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RAS-MAPK inhibition halts spinal deformity in neurofibromatosis type 1 mouse model
Spinal deformities such as scoliosis and kyphosis are among the most serious complications of neurofibromatosis type 1 (NF1), a genetic disorder that affects about one in 3,000 people.
Immune checkpoint therapy (ICT) is a front-line treatment for lung cancer; however, low mutational burden and ‘non-T cell inflamed’ signatures predict poor responses to ICT in ~50% of patients.
Fresh from raising $200 million, Colossal Biosciences announced it has genetically engineered the Colossal Woolly Mouse, with a warm coat taken from the genes of the extinct woolly mammoth. Dallas and ...
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