Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

A study of rare gene mutations that cause hereditary Alzheimer's disease shows these mutations disrupt production of a small sticky protein called amyloid. A University of Kansas study of rare gene ...

A University of Kansas study of rare gene mutations that cause hereditary Alzheimer's disease shows these mutations disrupt production of a small sticky protein called amyloid. Plaques composed of ...

Cabinet Peaks Medical Center is proud to offer a convenient, affordable, and accurate genetic testing option for men and ...

Hereditary spastic paraplegia (HSP) comprises a heterogeneous group of neurodegenerative disorders that are mainly characterised by progressive spasticity and weakness of the lower limbs. Recent ...

For 10% of colorectal cancer patients, hereditary factors play a role, with higher percentages among younger patients.

Pheochromocytomas and paragangliomas are rare neuroendocrine tumors with a strong hereditary component. Half the genes whose alterations confer hereditary susceptibility to develop this condition code ...

An expert in the field revealed how genetic testing works, what it means and what steps to take if your family history points to an elevated risk of cancer. Genetic testing, as the name suggests, ...

Please provide your email address to receive an email when new articles are posted on . The patient, aged 66 years, had no previous edema. The patient tested positive for a mutation in the plasminogen ...

Art shows synaptic degeneration triggered by stalled γ-secretase enzyme-substrate complexes. Proteolytic processing by membrane-embedded γ-secretase produces amyloid β-peptides that are implicated in ...