New antivirals are being tested for herpesviruses, and scientists now know how they work

Harvard Medical School researchers have uncovered crucial insights into how an emerging class of antiviral drugs works.
Harvard Medical School

Researchers Now Understand How a New Class of Antivirals Works

Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...
EurekAlert!

Targeting viral enzymes to strengthen brain immunity against HSV-1

Inhibiting the herpes simplex virus type 1 viral enzyme uracil-DNA glycosylase reactivates the natural defense protein apolipoprotein B mRNA editing enzyme, catalytic polypeptide-1 (APOBEC1) in the ...
KPBS

Genital herpes is a 'forgotten' virus. But that doesn't mean it's gone away.

Genital herpes infections are very common. There are 42 million new infections each year — that averages out to one new person infected each second. While treatments can help with symptoms, there's no ...
Medical Xpress

Modified herpes virus helps destroy glioblastoma in preclinical models

Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, ...