A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

Scientists have uncovered a gut-specific epigenetic aging mechanism that links inflammation and iron imbalance to cancer risk ...

Although the gut renews itself constantly, its stem cells accumulate age-related molecular changes that quietly alter how ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Bowel cancer risk is influenced by several overlapping factors including age, weight and inflammation. This study is early stage biology, but it strengthens the idea that long term gut health is ...

The human gut replaces its cells faster than any other tissue in the body. Every few days, fresh cells are produced by specialized stem cells that ...

Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy. By targeting senescent ...

Support cells surrounding stem cells rather than stem cells alone, are far more vulnerable to ageing and may hold the key to understanding how tissues age and lose their generative capacity.

Indian scientists found that aging is driven by failing "support cells" rather than stem cells themselves. Deteriorating ...

As people live longer, the gut quietly accumulates damage that can tip the balance between healthy tissue renewal and chronic ...