Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

Over the past decade, developing nanochannels with valence selectivity for cations have attracted increasing attention due to their potential role in a wide range of technological applications such as ...

(Left) K+ ion (magenta sphere) is shown bound in the S2 site of the selectivity filter (green ribbon). The backbone carbonyl groups of the S2 site are shown as spheres. (Right) View looking down the ...

Potassium channels are responsible for the selective permeation of K⁺ ions across cell membranes. K⁺ ions permeate in single file through the selectivity filter, a narrow pore lined by backbone ...