One of the Most Common Diabetes Treatments May Be Making the Disease Worse, Study Warns

A new study suggests that one of the most common diabetes treatments may speed type 2 diabetes progression by causing insulin-producing cells to lose their functional identity. Sulphonylureas have bee ...
News Medical

Bioactive small molecules enhance CRISPR/Cas9 loss-of-function editing in human cells

In a recent Molecular Therapy: Nucleic Acids study, researchers demonstrate enhanced loss-of-function editing of clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated ...
News Medical

Omicron spike N679K mutation acts as a loss-of-function mutation attenuating SARS-CoV-2 in vitro & in vivo

In a recent study posted in the bioRxiv* preprint server, researchers explored the impact of a loss-of-function mutation in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron ...

Stroke and dementia: Combating loss of function in small vessels of the brain

A new study identifies molecular factors that promote small vessel disease—and an active drug that can restore impaired vascular functions.
Healthline

Ozempic Can Cause Major Loss of Muscle Mass and Reduce Bone Density

Share on Pinterest Weight loss medications like Ozempic and Wegovy can help people drop pounds quickly, but they can also cause a rapid loss of muscle mass and bone density unless lifestyle changes ...
The University of Chicago Chronicle

Rapid loss of smell predicts dementia and smaller brain areas linked to Alzheimer’s

Though we often undervalue our ability to smell compared to our abilities to see and hear, our olfactory sense provides our brain with critical information, from detecting potential dangers like smoke ...