“With the high-speed AFM we could, for the first time, peer inside native nuclear pore complexes only forty nanometers in size,” study coauthor Roderick Lim of the University of Basel said in a ...

Nuclear pore complexes are more dynamic than previously thought, reshaping our understanding of a vital transport process in cells. An international study led by the University of Basel (Switzerland) ...

Nuclear pore complexes (NPCs) are channels composed of multiple proteins that ferry molecules in and out of the nucleus, regulating many critical cellular functions, such as gene expression, chromatin ...

Researchers at Kanazawa University report in Cell Reports how alterations in the nuclear pores lead to the degradation of anti-tumor proteins. Several types of cancer are believed to be linked to ...

The human NPC is composed of approximately 34 nucleoporin proteins. The interior, or “symmetric,” core is composed of an inner ring, and two outer rings that sit on either side of the nuclear envelope ...

Because viruses have to hijack someone else’s cell to replicate, they’ve gotten very good at it—inventing all sorts of tricks. A new study from two University of Chicago scientists has revealed how ...

If the cell nucleus is like a bank for DNA, nuclear pores are the security doors around its perimeter. Yet more security doors aren't necessarily better: some cancer cells contain a dramatic excess of ...