Lenvatinib and pembrolizumab in patients with metastatic papillary renal cell carcinoma: A phase 2 pilot study. Differences in the expression heterogeneity of ADC-related markers between primary ...
6don MSN
New method reveals how mutations drive transthyretin amyloidosis and guides precision drug design
An international research team reveals new molecular mechanisms associated with pathogenic mutations in the protein ...
Up to 5% of Americans may carry genetic variants associated with cancer risk, according to a cross-sectional analysis.The ...
About The Study: This study identified 5.05% of individuals carrying pathogenic or likely pathogenic variants, suggesting a higher-than-expected prevalence of key cancer susceptibility genes in a ...
Hosted on MSN
Somatic and germline mutation rates covary linearly across ciliates and mammals, study finds
In a study published in Current Biology on August 14, Prof. Miao Wei's team at the Institute of Hydrobiology (IHB) of the Chinese Academy of Sciences and Prof. Zhang Jianzhi's team at the University ...
More evidence points to the benefits of germline genetic testing for patients with various cancers. Such testing can identify mutations that may warrant a change of treatment and allow trying a ...
Germline pathogenic variants contribute to 15%-20% of ovarian cancer cases, with BRCA1/2 mutations accounting for 65%-85% of these cases. Disparities in genetic testing uptake exist across racial, ...
About The Study: In this secondary analysis of the WISDOM trial, a randomized clinical trial that enrolled women without breast cancer ages 40 to 74, criteria-independent genetic testing in a ...
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