Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located.

A collaborative project led by St. Jude Children’s Research Hospital has created a comprehensive guide to help standardize ...

The liver is remarkable for its ability to regenerate after injury, yet when this process fails, acute liver failure (ALF) carries devastating outcomes. Traditional research methods, reliant on bulk ...

Spatial transcriptomics provides a unique perspective on the genes that cells express and where those cells are located.

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Correlation of enriched specific subset of immune cells nearby tumor associated macrophage (TAM) with pathologic complete response (pCR) of concurrent chemoradiotherapy followed by nivolumab in ...

Single-cell genome sequencing techniques have recently emerged, enabling high-throughput transcriptome profiling at the level of individual cells. Among ...

Scientists have discovered, for the first time, how root cells respond to their complex soil environment, revealing that roots actively "sense" their microenvironment and mount precise, cell-specific ...

A technology that combines transcriptomic data and AI enables a novel approach to drug discovery based on the state of cells, how they behave and which genes they express. The Drugreflector model, ...