How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...
Engineered mRNA has turned cells into tiny biofactories, producing medications to successfully treat an inflammatory skin condition and two types of cancer, according to a new study. The tech paves ...
Arizona State University scientists have discovered an unprecedented pathway in a fungus to produce telomerase RNA (TER) from a protein-encoding messenger RNA (mRNA). Unlike in animals and other fungi ...
Raina Biosciences published data from its generative AI platform in a study, “Deep generative models design mRNA sequences with enhanced translational capacity and stability,” recently published in ...
This is a preview. Log in through your library . Abstract Loss of the fragile X mental retardation protein (FMRP) causes fragile X syndrome (FXS). FMRP is widely thought to repress protein synthesis, ...
The Nobel Committee has awarded the 2023 Nobel Prize in Physiology or Medicine to Katalin Karikó and Drew Weissman for their pioneering work in the development of mRNA vaccine technology, which made ...
Therapeutic mRNAs offer great potential as a versatile and precise tool against cancer and other diseases. However, the therapeutic effectiveness is limited by the poor translation uptake of naked ...
A cancer vaccine based on the messenger RNA (mRNA) technology, provided alongside the checkpoint inhibitor pembrolizumab (Keytruda), has shown encouraging results in an open label phase 2b clinical ...
(Nanowerk Spotlight) COVID-19 is a game changer for both nanomedicine and nucleic acid-based vaccines. Just two years ago, there were no licensed messenger RNA (mRNA) vaccines; today Pfizer-BioNTech ...
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