The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

Chromosomes are thread-like structures located inside the nucleus of animal and plant cells. Each chromosome is made of protein and a single molecule of deoxyribonucleic acid (DNA). Passed from ...

Researchers at Rice University are making strides in understanding how chromosome structures change throughout the cell's life cycle. Their study on motorized processes that actively influence the ...

We are entering into an exciting era of genomics where truly complete, high-quality assemblies of human chromosomes are available end-to-end, or from ‘telomere-to-telomere’ (T2T). Recently, the ...

This is a preview. Log in through your library . Abstract We have used light microscopy and serial thin-section electron microscopy to visualize intermediates of chromosome decondensation during G1 ...

During sexual reproduction, haploid gametes (i.e. eggs and sperm) are generated from diploid precursors through the specialized cell division of meiosis. Meiosis reduces ploidy by following one round ...

Researchers have made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides. Mistakes in ...

Holocentric chromosomes have evolved independently from X-shaped monocentric chromosomes multiple times in both animals and plants, but the mechanism behind the centromere-type transition is unknown.

In high school textbooks, human chromosomes are pictured as wonky Xs like two hotdogs jammed together. But those images are far from accurate. "For 90 percent of the time," said Jun-Han Su, ...

One of the challenges of working with ancient DNA samples is that damage accumulates over time, breaking up the structure of the double helix into ever smaller fragments. In the samples we've worked ...