Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

There are only about 20,000 different genes in the human genome, yet our bodies are filled with an incredible diversity of cell types performing innumerable functions. The key to that diversity in ...

Scientists have pinpointed precise regions in the human genome where DNA is most likely to develop a mutation. At spots where RNA polymerase 'opens' your DNA to read and copy instructions – known as ...

A new study reports that the locations where genes begin are particularly prone to mutations, and these genetic changes can ...

A genomic analysis shows that transcription start sites are 35% more mutation-prone than expected, making them one of the genome’s most vulnerable regions. Many of these errors arise as mosaic ...

Comparison of a single-stranded RNA and a double-stranded DNA with their corresponding nucleobases. (Image: Wikimedia Commons, CC SA 3.0) The most common type of base pairing is the Watson-Crick base ...