Metabolic dysfunction-associated steatohepatitis (MASH) is a polygenic disorder influenced by multiple genes, but their specific roles in the progression of disease remain unknown. To address this gap ...

A newly identified receptor rolls out the red carpet for α-synuclein fibrils, ushering them inside neurons and fast-tracking their spread, according to research from Fudan University, Shanghai. In the ...

Multigene families are at the core of immune system complexity, shaping how organisms sense, respond to, and remember infection. Gene duplication, ...

Researchers from the Baylor College of Medicine have characterized 100 conserved Alzheimer’s disease (AD) risk orthologue genes in Drosophila and found several with unknown roles in brain structure, ...

Researchers studied data from a million people and found evidence that a height gene shared by both sexes is amplified in men. By Gina Kolata Men are taller than women, by an average of about five ...

A new study suggests that the NOVA1 gene may have been a key player in the evolution of human language. By Carl Zimmer Scientists have long struggled to understand how human language evolved. Words ...

Letasha (left) and Kristina (center) both have COPA syndrome. Their mother, Betty (right), has the same disease mutation in the COPA gene, but is healthy thanks to having the HAQ-STING gene. UCSF ...

Ancient DNA is telling us more and more about humans and environments long past. Could it also help rescue the future? Eske Willerslev was on a tour of Montreal’s Redpath Museum, a Victorian-era ...

Neanderthals died out around 40,000 years ago, but a new study reveals that their genetic legacy continues to influence our brains today. Chiari malformation type 1 is a rare brain condition where the ...

Nwd1 deletion disrupts sarco/endoplasmic reticulum calcium ATPase (SERCA2) activity, which leads to heightened endoplasmic reticulum stress, contributing to metabolic dysfunction-associated ...