Researchers at the Department of Cell and Molecular Biology, Karolinska Institutet have captured the first detailed molecular snapshots of human polynucleotide phosphorylase (hPNPase) in action, ...
Many enzymes have non-canonical or non-enzymatic functions. Therefore, these enzymes can still be functional when their activity is compromised, such as after inhibition with an active site inhibitor ...
The enzyme PI3K plays a critical role in cell migration. Scientists have long understood this function. But researchers have recently unveiled that a subunit of this enzyme also has the ability to ...
Enzymes that cut DNA at specific sites are called endonucleases; these enzymes play many roles in genomic replication, fidelity, and defense. The initial discovery of restriction endonucleases in the ...
Photodynamic therapy (PDT), characterized by its non-invasive nature and precise spatiotemporal selectivity, has garnered considerable attention for its applications in tumor and anti-infection ...
Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...
Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic Resonance (NMR) spectroscopy which shows how different parts of complex ...
Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a ...
An international research team has published a study in the journal The FEBS Journal that significantly advances the knowledge of a rare hereditary metabolic disease: classical homocystinuria. The ...
Researchers from the Cluster of Excellence Balance of the Microverse at the University of Jena and the Leibniz-HKI, together ...
One of the most revolutionary discoveries of the century, the CRISPR gene-editing system is built on a bacterial defense mechanism that allows scientists to make precise edits to DNA. Now scientists ...