Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a ...

The mammalian elongation complex has remained a mystery – until researchers discovered how it controls its speed.

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Scientists at the Massachusetts Institute of Technology (MIT) have invented a new single-cell nascent RNA sequencing technique that lets them observe the timing of gene and enhancer activation in ...

Proteins are essential biological molecules that perform a vast array of functions crucial for life, from catalyzing biochemical reactions and transporting molecules to providing structural support ...