When RNA malfunctions, it can result in cancer and developmental disorders. Our cells have molecular “machines” that keep RNA “in check” and eliminate RNAs at the right time. Most come equipped with a ...

A study captured the first near frame-by-frame view of a self-splicing ribozyme assembling into its active form. Using ...

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

microRNAs (miRNA) are recently discovered, short segments of RNA, which play vital roles in health and disease. microRNA over- or under-abundance can switch critical disease genes on or off, ...

Spatial RNA medicine combines transcriptomics and RNA therapeutics, mapping gene expression in tissues to enhance precision ...

Obelisks are <1 kb RNA replicators with protein-coding genes and ribozymes * Found in 50% of oral and 7% of gut microbiomes, indicating widespread presence * Their impact on //human health remains ...

Shape Therapeutics has raised $112 million in series B financing to further develop RNA editing and gene-therapy technologies. Shape’s RNA editing technology takes advantage of an enzyme called ADAR ...

(Reuters Health) - Online gamers have uncovered better models for folding RNA molecules than supercomputers housed in some of the world’s most prestigious research labs, according to a new report. The ...

Roche has agreed to license Shape Therapeutics’ RNA-editing technology in a deal worth up to $3 billion. Shape uses adeno-associated viruses to deliver RNA-editing machinery to treat neurological and ...

Biologists at Indiana University Bloomington have shown that the surfaces of plant leaves are coated with a diverse array of RNA molecules. The finding suggests that the RNA present on the leaf ...