Mapping of Z-DNA in the genome by deep learning has revealed a number of different roles for Z-DNA in health and disease The transformer algorithm maps Z-DNA with high accuracy and precision. The ...

In a new study, scientists have identified a small molecule candidate drug that triggers the formation of left-handed Z-DNA in cells that in turn activates a highly immunogenic programmed pathway of ...

Plants and animals have genomes made of four nucleotide bases, adenine (A), thymine (T), cytosine (C), and guanine (G). But there's another genetic 'letter' that's been identified; in 1977 a virus ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

These viruses use a unique genetic alphabet not found anywhere else on the planet. When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. The blueprint ...

Scientists have identified sequences in great apes' DNA capable of forming unconventional structures called non-B DNA. These configurations appear to play a key role in regulating cellular processes ...

In a paper published in the May 13th, 2021 issue of PLOS Genetics, a Z-RNA nanoswitch that regulates interferon immune responses is described. The switch, less than 5 nanometer in length, is based on ...