High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...
An international research team has identified a human protein, ANKLE1, as the first DNA-cutting enzyme (nuclease) in mammals ...
Researchers discovered that a tiny structural feature of the enzyme GPX4 helps keep neurons safe. A rare mutation removes ...
Figure 1. ANKLE1 senses mechanical tension in DNA and helps resolve DNA bridges connecting separating daughter nuclei. ANKLE1 ...
Chemists have long been fascinated and frustrated by saxitoxin: a molecule that causes temporary paralysis by blocking the ...
This paper aims to critique the argument constructed by Anna Smajdor and Joona Räsänen that pregnancy is a disease. Their argument that pregnancy fits the features of disease they enumerate stems from ...
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Gut microbe metabolite TMA improves blood sugar by shutting down a key inflammatory switch
Researchers identified trimethylamine (TMA) as a gut microbe–derived metabolite that directly inhibits IRAK4 to reduce ...
In November 2025, IARC, through the World Health Organization, designated the endocrine-disrupting herbicide atrazine as ...
Two years after this, Sakaguchi was able to link these discoveries. He proved that the Foxp3 gene governs the development of ...
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